Uses of Plain Gut Fast Absorbable Suture and How They Differ From Plain Gut Suture

Fast absorbing surgical gut suture is a strand of collagenous material prepared from the sub mucosal layers of the small intestine of healthy sheep, or from the layers of the small intestine of healthy cattle. Fast absorbing surgical gut sutures are sterile and elicit only a slight to minimal tissue reaction during absorption. Fast absorbing surgical gut sutures differ from U.S.P. minimum strength requirements by less than thirty percent. Fast absorbing surgical gut sutures are intended for dermal suturing only. They should be utilized only for external knot tying procedures.

The results of implantation studies of fast absorbing surgical gut sutures in the skin of animals indicate that nearly all of its original strength is lost within approximately seven days of implantation. When surgical gut suture is placed in tissue, a moderate tissue inflammation occurs which is characteristic of the foreign body response to a substance. This is followed by a loss of tensile strength followed by a loss of suture mass, as the enzymatic digestive process dissolves the surgical gut. This process continues until the suture is completely absorbed. Many variable factors may affect the rate of absorption.  Data obtained from implantation studies in rats show that the absorption of these sutures is essentially complete by the twenty first to forty second post implantation day.

Users should be familiar with surgical procedures and techniques involving gut suture before using fast absorbing surgical gut suture for wound closure, as the risk of wound dehiscence may vary with the site of application and the suture material used. The use of this suture may be inappropriate in elderly, malnourished, or debilitated patients, or in patients suffering from conditions which may delay wound healing. As this is an absorbing material, the use of supplemental non absorbable sutures should be considered by the surgeon in the closure of sites which may undergo expansion, stretching or distention or which may require additional support. As an absorbable suture, fast absorbable surgical gut may act transiently as a foreign body. Acceptable surgical practice should be followed in the management of contaminated or infected wounds.

Adverse effects associated with the use of this fast absorbable surgical gut include wound dehiscence, variable rates of absorption over time (depending on such factors as the type of suture used, the presence of infection and the tissue site), failure to provide adequate wound support in closure of sites where expansion, stretching or distention occur, etc., unless additional support is supplied through the use of non-absorbable suture material, failure to provide adequate wound support in elderly, malnourished or debilitated patients or in patients suffering from cancer, anemia, obesity, diabetes, infection or other conditions which may delay wound healing, allergic response in patients with known sensitivities to collagen which may result in an immunological reaction resulting in inflammation, tissue granulation or fibrosis, wound suppuration and bleeding, as well as sinus formation, infection, moderate tissue inflammatory response characteristic of foreign body response, and calculi formation in urinary track when prolonged contact with salt solutions such as urine and bile occurs, and transitory local irritation at the wound site. 

 

Fast absorbing surgical gut sutures are only available in sizes 5-0 (metric size 1.5) and 6-0 (metric size 1.0) both with a PC-1 cutting needle which is thirteen millimeters in diameter. They are made by Ethicon and their item code numbers are 1915G for 5-0 and 1916G for 6-0.